Unlocking the Benefits of Polynucleotide Skin Treatments
- Elevated Magazines

- Oct 22
- 5 min read

Do you dream of achieving youthful skin without invasive surgery?
Introducing the power of Polynucleotide skin treatment! In recent years, this advanced technique has gained significant attention and popularity, and for good reason.
Exciting developments in the aesthetics industry
Polynucleotide skin treatment is revolutionising the way people address their skin concerns and delivering amazing results.
One of the most attractive things about Polynucleotides is that it works from the inside out and actually repairs and regenerates the skin rather than just simply filling it out like traditional dermal fillers. This means real, visible results that actually last.
In this ultimate guide we'll cover:
The Science Behind Polynucleotides
How They Work To Transform Your Skin
What Results Can You Actually Expect?
Who is Suitable for Polynucleotide Skin Treatment?
What Are Polynucleotides, Anyway?
Polynucleotides are injectable bio-stimulators.
They are made up of purified DNA fragments.
Some of the recent press has called them the "salmon sperm facial"… and there is some truth to that. Polynucleotides are often sourced from wild salmon DNA. But don't let that put you off…
The reason we know these molecules are so biocompatible with human skin is that our DNA structure is almost identical.
When injected, Polynucleotide treatments stimulate a whole host of regenerative processes under the skin, helping to target multiple signs of ageing at the same time.
The amazing part is:
Polynucleotide skin treatments work by:
Stimulating collagen and elastin production
Improving tissue regeneration
Restoring skin tone and elasticity
Reducing inflammation
Improving skin hydration from within
The great thing about this is that it all happens through your own skin's natural repair mechanisms.
So what makes Polynucleotide skin treatments so different?
Traditional aesthetic treatments tend to be single function…
They either add volume, or temporarily paralyse muscles. Polynucleotide skin treatment is completely different. They work at the cellular level to change the way the skin functions.
Here's a simple way to understand how this compares to traditional aesthetic treatments…
Fillers fill the space below your skin. Polynucleotides send signals to your cells, essentially instructing them to repair and regenerate themselves. The result is a much more natural, longer lasting improvement in the skin.
The reason you will see continued improvement over time is that the more the treatment is administered, the more your own cells respond to it, producing more collagen, and thus skin quality continues to get better and better over the following months.
Studies have shown that patient satisfaction after treatment is moderate to high, and patients reported that treatment was well tolerated.
What are the Real Benefits You Can See?
Ok, so you've had a little science lesson… But what is it that the Polynucleotide skin treatment actually does to help your skin?
We'll break it down for you…
Minimises wrinkles and fine lines
The reason so many people love Polynucleotide treatments is for the anti-ageing effects.
Polynucleotides are proven to help smooth wrinkles and fine lines, and help visibly reduce the depth of wrinkles. The results are completely natural, and are the result of improving the quality of the skin.
This is not just an effect of paralysing your facial muscles like botox, it's an actual, long-term improvement in skin quality.
Enhances the overall skin texture and tone
One of the benefits people love most is the incredible difference to their skin texture after a treatment.
Polynucleotide skin treatments are brilliant for improving the overall feel and tone of your skin.
Polynucleotides help to even out your skin texture, by encouraging cell turnover and regeneration.
They also improve melanocyte activity, and can help to even out pigmentation and create a smoother, more uniform skin tone.
Improve hydration
Polynucleotide skin treatment doesn't just help the look and feel of your skin on the surface, it also goes a long way towards helping to hydrate your skin from the inside out.
The molecules encourage your skin to better retain moisture, leading to a more hydrated, dewy glow.
Hydrated, plump skin is the key to giving the appearance of a naturally radiant complexion. If you have dull, dehydrated skin this treatment can be life changing.
Targeting specific areas of concern
A lot of people have very specific problem areas they would like to address…
Areas such as around the eyes can be notoriously difficult to treat with most other aesthetic procedures.
Polynucleotides can be used very effectively in the under-eye area, to help address:
Dark circles
Hollow under-eyes
Crepey eyelid skin
Crow's feet and lines around the eyes
They can also be used on other areas of the face, neck and hands.
How quickly can you expect to start seeing results?
If you are impatient like us, the next question is always…
When can I expect to start seeing results?
In most people results start to become apparent 2-3 weeks after treatment.
What's really interesting about this treatment though is that as the months go by, your own cells continue to respond and produce more collagen and elastin in the treated areas, meaning that the results keep improving as time goes by. The full effect is generally around 3 months post treatment.
To get the best results:
Most experts would recommend having 2 or 3 sessions
With 2-4 weeks between each session
And results can last 6-12 months or longer
The size of the market for these treatments is expected to grow significantly.
The global polynucleotides injectable market size reached $127.6 million in 2024 and is expected to register a robust growth over the next few years.
Who is suitable for Polynucleotide skin treatment?
This treatment can work well for most people looking to improve the look and feel of their skin.
You are an ideal candidate if:
You want natural looking skin rejuvenation.
You have fine lines and wrinkles.
You are experiencing loss of elasticity.
Your skin is dull or dehydrated.
You want to address under-eye concerns.
You are looking for minimally invasive treatments.
Polynucleotides are particularly effective in their 30s and 40s, who want to start to address early signs of ageing.
However, they can also help to provide significant improvement for those in their 50s and 60s, where the skin may be older and in need of more intensive regeneration.
Side Effects
What about side effects?
One of the reasons Polynucleotides are gaining so much traction is that there are usually very few and if present they are mild and temporary.
Most people will experience only a few minor side effects like temporary redness, some slight swelling, or minor bruising around injection sites.
Side effects tend to resolve within a couple of days.
Rarely are there any serious side effects if the treatment has been performed by a qualified practitioner.
Another advantage of this is that downtime is minimal.
Most people can return to their normal day-to-day activities immediately after treatment.
Making The Investment
Polynucleotide skin treatment is a truly significant breakthrough in aesthetics.
It is bridging the gap between quick fixes that only last a few weeks, and more invasive surgical procedures.
Polynucleotides work hand in hand with your body's own natural regeneration processes to provide a much safer, more natural approach to skin rejuvenation.
Results are stunning.
Enhanced skin texture, visible reduction in wrinkles, improved elasticity and hydration, all work together to create a more youthful, radiant complexion.
The key is to find a qualified, experienced practitioner who knows how to use these treatments effectively, and tailor the treatment plan to your specific concerns and skin type.
Wrapping up.
Polynucleotide skin treatment is a game-changer.
It's not just about covering up the signs of aging. It's about addressing the root causes and stimulating your skin's natural ability to repair and regenerate itself.
The result? Visible improvement in skin quality that continues to develop over the following months.
If you've tried traditional aesthetic treatments without success, or you're looking for a more natural, effective anti-ageing approach, then Polynucleotides could be the missing piece of the puzzle for you.
The science is there, the results are incredible, and the treatment is continuing to get more and more advanced as practitioners perfect new techniques and methods.
It's no wonder this is one of the hottest treatments in the aesthetic industry right now!
